Etoposide
اتوپوزید
🎗️ Antineoplastic And Immunomodulating AgentsTopoisomerase II inhibitor
Market / country: 🇺🇸 USA
Toposar (US)
🧮 Dose calculator
Testicular cancer · Regimen source: FDA Etoposide · Dosage and Administration
- • Or 100 mg/m²/day on days 1, 3 and 5. Repeat courses every 3–4 weeks after recovery. Renal impairment per Precautions. FDA Etoposide · Dosage and Administration
- • Only under an oncologist in an equipped centre. Calculator = label mg/m² × BSA (Mosteller); protocol, cycle interval and adjustment for CBC and renal/hepatic function rest with the oncology team. FDA Etoposide · Dosage and Administration
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Previous hypersensitivity to etoposide or any component. FDA Etoposide · Contraindications
Warnings
- • Boxed warning: severe myelosuppression with infection or bleeding. FDA Etoposide · Warnings
Formulations
- 20 mg/mL (100 mg/5 mL, 500 mg, 1 g) — injection 🇺🇸 USA FDA Etoposide · How Supplied
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Etoposide · Pregnancy
“Etoposide can cause fetal harm when administered to a pregnant woman.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Etoposide · Nursing Mothers
“Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from etoposide, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Etoposide · Pediatric Use
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Etoposide · Geriatric Use
“Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function (see PRECAUTIONS , Renal Impairment for recommended dosing adjustments in patients with renal impairment).”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA074983
- DailyMed (FDA label)FDA Etoposide
- MedlinePlus (NIH)EtoposideEtoposide Injection
- WHO ATC/DDDL01CB01
- Darooyab (Iran)Etoposide
🇮🇷 Registered in Iran Darooyab · G-996/Etoposide
Dosage forms with Iranian generic codes, per Darooyab.
- 00517 · ETOPOSIDE 100MG CAP · کپسول اتوپوزاید ۱۰۰ میلیگرم
- 00518 · ETOPOSIDE 100MG/5ML AMP · آمپول اتوپوزاید ۱۰۰ میلیگرم / ۵ میلیلیتر
- 18934 · ETOPOSIDE 200MG/10ML VIAL · ویال اتوپوزاید ۲۰۰ میلیگرم / ۱۰ میلیلیتر
- 00519 · ETOPOSIDE 25MG CAP · کپسول اتوپوزاید ۲۵ میلیگرم
- 18730 · ETOPOSIDE 50MG VIAL · ویال اتوپوزاید ۵۰ میلیگرم
- 00520 · ETOPOSIDE 50MG CAP · کپسول اتوپوزاید ۵۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Etoposide · How SuppliedFDA Etoposide · Dosage and AdministrationFDA Etoposide · ContraindicationsFDA Etoposide · WarningsFDA Etoposide · SPL approval / marketing categoryFDA Etoposide · PregnancyFDA Etoposide · Nursing MothersFDA Etoposide · Pediatric UseFDA Etoposide · Geriatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-996/Etoposide
- Clinical review⚠ Unverified