Erlotinib

ارلوتینیب

⚠ Unverified

🎗️ Antineoplastic And Immunomodulating AgentsEGFR inhibitor

Market / country: 🇺🇸 USA

Tarceva (US)

🧮 Dose calculator

Lung cancer (small-cell and non-small-cell) · Regimen source: FDA Erlotinib · 2.2

  • • Only under an oncologist; continue until progression or unacceptable toxicity. Dose adjustments for toxicity and interactions per label. FDA Erlotinib · 2.2

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🛡️ Safety & information

Warnings

  • • Interstitial lung disease; renal failure; hepatotoxicity; GI perforation; bullous skin disorders; stroke; microangiopathic haemolytic anaemia; ocular disorders; bleeding with warfarin; embryo-fetal toxicity. FDA Erlotinib · 5

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Erlotinib · 8.1

    “Risk Summary Based on animal data and its mechanism of action, erlotinib can cause fetal harm when administered to a pregnant woman.”
  • 🤱 BreastfeedingDangerous / avoid

    Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Erlotinib · 8.2

    “Advise a lactating woman not to breastfeed during treatment with erlotinib tablets and for 2 weeks after the final dose.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Erlotinib · 8.4

    “The safety and effectiveness of erlotinib in pediatric patients have not been established.”
  • 👴 Older adultsNo specific problem stated

    Label: no specific difference or dose adjustment stated for older adults. FDA Erlotinib · 8.5

    “No overall differences in safety or efficacy were observed between subjects 65 years and older and those younger than 65.”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Erlotinib · 8.3

    “Contraception Females Erlotinib can cause fetal harm when administered to a pregnant woman [see Use in Specific Populations ( 8.1 )] .”

📚 Reference status for this drug

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