Methyldopa
متیلدوپا
❤️ Cardiovascular SystemCentral alpha-2 agonist
Market / country: 🇺🇸 USA
Aldomet (US)
🧮 Dose calculator
Hypertension · Regimen source: FDA Methyldopa · Dosage and Administration — Adults
- • Maintenance 500 mg–2 g in 2–4 doses; max 3 g/day. FDA Methyldopa · Dosage and Administration — Maintenance
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Active liver disease (acute hepatitis, active cirrhosis); previous methyldopa liver disorder; MAO inhibitors; hypersensitivity. FDA Methyldopa · Contraindications
Monitoring
- • Positive Coombs test and haemolytic anaemia; liver tests in the first weeks. FDA Methyldopa · Warnings
Formulations
- 250 mg tablet — tablet 🇺🇸 USA FDA Methyldopa · How Supplied
- 500 mg tablet — tablet 🇺🇸 USA FDA Methyldopa · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Methyldopa · Pregnancy
“Because animal reproduction studies are not always predictive of human response, methyldopa should be used during pregnancy only if clearly needed.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Methyldopa · Nursing Mothers
“Therefore, caution should be exercised when methyldopa is given to a nursing woman.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Methyldopa · Pediatric Use
“There are no well-controlled clinical trials in pediatric patients.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Methyldopa · Geriatric Use
“Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection and it may be useful to monitor renal function.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA070076
- DailyMed (FDA label)FDA Methyldopa
- MedlinePlus (NIH)Methyldopa
- WHO ATC/DDDC02AB01
- Darooyab (Iran)Methyldopa
🇮🇷 Registered in Iran Darooyab · G-1761/Methyldopa
Dosage forms with Iranian generic codes, per Darooyab.
- 11408 · METHYL DOPA 500MG TAB · قرص متیل دوپا ۵۰۰ میلیگرم
- 00832 · METHYLDOPA 250MG TAB · قرص متیلدوپا ۲۵۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Methyldopa · How SuppliedFDA Methyldopa · Dosage and Administration — AdultsFDA Methyldopa · Dosage and Administration — MaintenanceFDA Methyldopa · Dosage and Administration — Pediatric PatientsFDA Methyldopa · ContraindicationsFDA Methyldopa · WarningsFDA Methyldopa · PregnancyFDA Methyldopa · Nursing MothersFDA Methyldopa · Pediatric UseFDA Methyldopa · Geriatric UseFDA Methyldopa · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1761/Methyldopa
- Clinical review⚠ Unverified