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Mucormycosis
Mucormycosis · ICD-10: B46.9
Symptoms
- • Rhinocerebral (common in uncontrolled diabetes): swollen, protruding eyes, dark scabs in the nose
- • Sinus pain or congestion and redness of the skin over the sinuses
- • Fever, headache, mental status changes
- • Pulmonary: cough, occasionally coughing blood, fever, shortness of breath
- • GI: abdominal pain, bloody stool or vomit
- • Skin: hardened, sometimes painful area with a blackened centre
Drugs and regimens
Amphotericin B (conventional deoxycholate)⚠ Unverified
Mucormycosis — start 0.25 mg/kg/day, increase to 0.5–0.7 mg/kg/day
Isavuconazonium (isavuconazole)⚠ Unverified
Invasive mucormycosis — adult: maintenance 372 mg once daily (after loading)
Isavuconazonium (isavuconazole)⚠ Unverified
Children (IV from 1 y, capsules from 6 y and 16 kg) — dose per label weight table