Sugammadex

🧮 Dose calculator

Reversal of neuromuscular blockade · Regimen source: FDA Bridion · 2.2

• • Based on actual body weight; timing and dose by TOF monitoring; single bolus. FDA Bridion · 2.1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Bridion · 8.1

  “Risk Summary There are no clinical trial data on BRIDION use in pregnant women to inform any drug-associated risks.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Bridion · 8.2

  “Risk Summary No data are available regarding the presence of sugammadex in human milk, the effects of sugammadex on the breast fed infant, or the effects of sugammadex on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Bridion · 8.4

  “The safety and effectiveness of BRIDION for reversal of neuromuscular blockade induced by rocuronium bromide or vecuronium bromide have been established in pediatric patients from birth and older.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Bridion · 8.5

  “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function [see Use in Specific Populations (8.6) , Clinical Pharmacology (12.3) ] .”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Bridion · 8.3

  “Contraception Upon administration of BRIDION, the efficacy of hormonal contraceptives may be reduced for up to 7 days.”