Neostigmine

🧮 Dose calculator

Reversal of neuromuscular blockade · Regimen source: FDA Neostigmine · 2.2

• • Only when the first TOF twitch is at least 10% of baseline. Atropine or glycopyrrolate before or with it (separate syringe). Children dosed as adults. FDA Neostigmine · 2.2FDA Neostigmine · 2.4FDA Neostigmine · 2.3

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Neostigmine · 8.1

  “Risk Summary There are no adequate or well-controlled studies of neostigmine methylsulfate injection in pregnant women.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Neostigmine · 8.2

  “Risk summary Neostigmine methylsulfate has not been studied in lactating women.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Neostigmine · 8.4

  “Neostigmine methylsulfate injection is approved for the reversal of the effects of non-depolarizing neuromuscular blocking agents after surgery in pediatric patients of all ages.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Neostigmine · 8.5

  “Because elderly patients are more likely to have decreased renal function, neostigmine methylsulfate injection should be used with caution and monitored for a longer period in elderly patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.