Doz

Reversal of neuromuscular blockade

Reversal of neuromuscular blockade · ICD-10: Z01.818

Drugs and regimens

Neostigmine⚠ Unverified

Reversal of shorter-acting NMBA, or first twitch well above 10% — 0.03 mg/kg

Neostigmine⚠ Unverified

Reversal of longer-acting NMBA, or first twitch near 10% — 0.07 mg/kg (max 5 mg)

Sugammadex⚠ Unverified

Moderate block (second TOF twitch reappeared) — 2 mg/kg

Sugammadex⚠ Unverified

Deep block (1–2 post-tetanic counts, no TOF response) — 4 mg/kg

Sugammadex⚠ Unverified

Immediate reversal ~3 min after rocuronium 1.2 mg/kg — 16 mg/kg (adults only)

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