Sotalol

سوتالول

⚠ Unverified

❤️ Cardiovascular SystemClass III antiarrhythmic (beta-blocker)

Market / country: 🇺🇸 USA

Betapace (US)

🧮 Dose calculator

Life-threatening ventricular arrhythmia · Regimen source: FDA Sotalol · 2.2

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🛡️ Safety & information

Contraindications

  • ⛔ Sinus bradycardia, sick sinus syndrome or 2nd/3rd-degree AV block without a pacemaker; long QT; cardiogenic shock or decompensated heart failure; serum potassium <4 mEq/L; bronchial asthma; hypersensitivity. FDA Sotalol · 4

Warnings

  • • Boxed warning: life-threatening proarrhythmia (torsade). Initiate and up-titrate in a facility with ECG monitoring and creatinine clearance calculation. FDA Sotalol · Boxed Warning

Renal adjustment

  • • eGFR < 60: Interval: CrCl 30–59 every 24 h; 10–29 every 36–48 h; <10 individualised. Escalate after at least 5 doses. FDA Sotalol · 2.5

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Sotalol · 8.1

    “Risk Summary Both the untreated underlying condition in pregnancy and the use of sotalol in pregnancy cause adverse outcomes to the mother and fetus/neonate (see Clinical Considerations) .”
  • 🤱 BreastfeedingDangerous / avoid

    Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Sotalol · 8.2

    “Because of the potential serious adverse reactions to the breastfed child and the high level of sotalol in breast milk, advise women not to breastfeed while on treatment with sotalol hydrochloride .”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Sotalol · 8.4

    “The safety and effectiveness of sotalol in children have not been established.”
  • 👴 Older adultsNo data

    The source for this drug has no section for this group.

  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Sotalol · 8.3

    “Infertility Based on the published literature, beta blockers (including sotalol) may cause erectile dysfunction.”

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