Selegiline
سلژیلین
🧠 Nervous SystemMAO-B inhibitor
Market / country: 🇺🇸 USA
Eldepryl (US)
🧮 Dose calculator
Parkinson's disease · Regimen source: FDA Selegiline caps · Dosage and Administration
- • With levodopa/carbidopa; after 2–3 days levodopa may be cut by 10–30%. Above 10 mg/day MAO-B selectivity is lost. FDA Selegiline caps · Dosage and AdministrationFDA Selegiline caps · Warnings
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to selegiline; meperidine (often extended to other opioids). FDA Selegiline caps · Contraindications
Warnings
- • Not above 10 mg/day (non-selective MAO inhibition); rare hypertensive reactions with tyramine-rich foods. FDA Selegiline caps · Warnings
Formulations
- 5 mg capsule — capsule 🇺🇸 USA FDA Selegiline caps · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Selegiline caps · Pregnancy
“Pregnancy Category C No teratogenic effects were observed in a study of embryo-fetal development in Sprague-Dawley rats at oral doses of 4, 12, and 36 mg/kg or 4, 12 and 35 times the human therapeutic dose on a mg/m 2 basis.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Selegiline caps · Nursing Mothers
“Because many drugs are excreted in human milk, consideration should be given to discontinuing the use of all but absolutely essential drug treatments in nursing women.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Selegiline caps · Pediatric Use
“The effects of selegiline hydrochloride in children have not been evaluated.”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA075321
- DailyMed (FDA label)FDA Selegiline caps
- MedlinePlus (NIH)SelegilineSelegiline Transdermal Patch
- WHO ATC/DDDN04BD01
- Darooyab (Iran)Selegiline
🇮🇷 Registered in Iran Darooyab · G-2499/Selegiline
Dosage forms with Iranian generic codes, per Darooyab.
- 01121 · SELEGILINE HCL 5MG TAB · قرص سلجیلین هیدروکلراید ۵ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Selegiline caps · How SuppliedFDA Selegiline caps · Dosage and AdministrationFDA Selegiline caps · WarningsFDA Selegiline caps · ContraindicationsFDA Selegiline caps · SPL approval / marketing categoryFDA Selegiline caps · PregnancyFDA Selegiline caps · Nursing MothersFDA Selegiline caps · Pediatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-2499/Selegiline
- Clinical review⚠ Unverified