Entacapone
انتاکاپون
🧠 Nervous SystemCOMT inhibitor
Market / country: 🇺🇸 USA
Comtan (US)
🧮 Dose calculator
Parkinson's disease · Regimen source: FDA Entacapone · Dosage and Administration
- • Always with levodopa/carbidopa; no antiparkinsonian effect alone. The calculator shows 4 doses; number of doses = number of levodopa doses. Levodopa dose may need reduction. FDA Entacapone · Dosage and Administration
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to entacapone. FDA Entacapone · Contraindications
Important interactions
- • Non-selective MAOIs (phenelzine, tranylcypromine): should not be combined. FDA Entacapone · Warnings
Formulations
- 200 mg tablet — tablet 🇺🇸 USA FDA Entacapone · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Entacapone · Pregnancy
“Pregnancy Category C.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Entacapone · Nursing Mothers
“Because many drugs are excreted in human milk, caution should be exercised when entacapone is administered to a nursing woman.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Entacapone · Pediatric Use
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA207210
- DailyMed (FDA label)FDA Entacapone
- MedlinePlus (NIH)Entacapone
- WHO ATC/DDDN04BX02
- Darooyab (Iran)Entacapone
🇮🇷 Registered in Iran Darooyab · G-2489/Entacapone
Dosage forms with Iranian generic codes, per Darooyab.
- 06428 · ENTACAPONE 200MG TAB · قرص انتاکاپون ۲۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Entacapone · How SuppliedFDA Entacapone · Dosage and AdministrationFDA Entacapone · ContraindicationsFDA Entacapone · WarningsFDA Entacapone · SPL approval / marketing categoryFDA Entacapone · PregnancyFDA Entacapone · Nursing MothersFDA Entacapone · Pediatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-2489/Entacapone
- Clinical review⚠ Unverified