Apomorphine

🧮 Dose calculator

Parkinson's disease · Regimen source: FDA Apokyn · 2.3

• • Always express the dose in mL. First dose under medical supervision. Start 0.1–0.2 mL. No second dose for the same off episode; at least 2 h apart. Trimethobenzamide 300 mg three times daily from 3 days before. Interruption >1 week: restart at 0.2 mL. Mild/moderate renal impairment: start 0.1 mL. FDA Apokyn · 2.1FDA Apokyn · 2.3FDA Apokyn · 2.5FDA Apokyn · 2.2FDA Apokyn · 2.4

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Apokyn · 8.1

  “Risk Summary There are no adequate data on the developmental risk associated with use of APOKYN in pregnant women.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Apokyn · 8.2

  “Risk Summary There are no data on the presence of apomorphine in human milk, the effects of apomorphine on the breastfed infant, or the effects of apomorphine on milk production.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Apokyn · 8.4

  “Safety and effectiveness in pediatric patients have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Apokyn · 8.5

  “In the APOKYN clinical development program, there were 239 patients less than age 65 treated with APOKYN and 311 patients who were age 65 or older.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.