Mannitol

مانیتول

⚠ Unverified

🩸 Blood And Blood Forming OrgansOsmotic diuretic

Market / country: 🇺🇸 USA

Osmitrol (US)

🧮 Dose calculator

Raised intracranial pressure and cerebral oedema · Regimen source: FDA Osmitrol · 2.2

  • • Preferably a central vein. Assess renal, cardiac and pulmonary status and correct electrolytes first; monitor osmolality. Not with blood products in the same set. FDA Osmitrol · 2.1FDA Osmitrol · 2.2

Enter age and weight.

🛡️ Safety & information

Contraindications

  • ⛔ Hypersensitivity to mannitol; anuria; severe hypovolaemia; severe pulmonary congestion or oedema; active intracranial bleeding (except during craniotomy). FDA Osmitrol · 4

Warnings

  • • Renal failure; CNS toxicity; fluid/electrolyte imbalance and hyperosmolarity; infusion-site reactions. FDA Osmitrol · 5

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Osmitrol · 8.1

    “Risk Summary The available case report data with mannitol over decades of use have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Osmitrol · 8.2

    “Risk Summary There are no data on the presence of mannitol in either human or animal milk, the effects on the breastfed infant, or the effects on milk production.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Osmitrol · 8.4

    “OSMITROL is approved for use in the pediatric population for the reduction of intracranial and intraocular pressure.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Osmitrol · 8.5

    “Evaluate the renal, cardiac and pulmonary status of the patient and correct fluid and electrolyte imbalances prior to administration of OSMITROL [see Warnings and Precautions (5.2 , 5.3 , 5.4 , 5.5 )].”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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