Brinzolamide
برینزولامید
👁️ Sensory OrgansCarbonic anhydrase inhibitor (ophthalmic)
Market / country: 🇺🇸 USA
Azopt (US)
🧮 Dose calculator
Open-angle glaucoma / ocular hypertension · Regimen source: FDA Azopt · 2
- • Shake well; separate other eye drops by at least 10 min. FDA Azopt · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to any component. FDA Azopt · 4
Warnings
- • Sulfonamide (severe sulfa reactions); corneal endothelium; not recommended in severe renal impairment; acute angle-closure glaucoma; contact lenses. FDA Azopt · 5
Formulations
- 1% eye suspension — eye drops 🇺🇸 USA FDA Azopt · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Azopt · 8.1
“Risk Summary There are no adequate and well-controlled studies in pregnant women to inform drug-associated risk.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Azopt · 8.2
“Risk Summary There are no data on the presence of brinzolamide in human milk, the effects on the breastfed infant, or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Azopt · 8.4
“A 3-month controlled clinical study was conducted in which AZOPT was dosed only twice a day in pediatric patients 4 weeks to 5 years of age.”
- 👴 Older adultsNo specific problem stated
Label: no specific difference or dose adjustment stated for older adults. FDA Azopt · 8.5
“No overall differences in safety or effectiveness have been observed between elderly and younger patients.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA020816
- DailyMed (FDA label)FDA Azopt
- MedlinePlus (NIH)Brinzolamide Ophthalmic
- WHO ATC/DDDS01EC04
- Darooyab (Iran)Brinzolamide
🇮🇷 Registered in Iran Darooyab · G-1566/Brinzolamide
Dosage forms with Iranian generic codes, per Darooyab.
- 01930 · BRINZOLAMIDE 1% OPH DROP · قطره چشمی برینزولامید ۱ درصد
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Azopt · 3FDA Azopt · 2FDA Azopt · 4FDA Azopt · 5FDA Azopt · SPL approval / marketing categoryFDA Azopt · 8.1FDA Azopt · 8.2FDA Azopt · 8.4FDA Azopt · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1566/Brinzolamide
- Clinical review⚠ Unverified