Dorzolamide + timolol eye drops
قطره چشمی دورزولامید + تیمولول
👁️ Sensory OrgansCarbonic anhydrase inhibitor + beta-blocker
Market / country: 🇺🇸 USA
Cosopt (US)
🧮 Dose calculator
Open-angle glaucoma / ocular hypertension · Regimen source: FDA Dorzolamide/timolol · 2
- • At least 5 minutes apart from other eye drops. FDA Dorzolamide/timolol · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Asthma or history of asthma, severe COPD; sinus bradycardia, 2nd/3rd-degree AV block, overt heart failure, cardiogenic shock; hypersensitivity. FDA Dorzolamide/timolol · 4
Formulations
- Dorzolamide 2% + timolol 0.5% eye drops — eye drops 🇺🇸 USA FDA Dorzolamide/timolol · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Dorzolamide/timolol · 8.1
“Dorzolamide hydrochloride and timolol maleate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Dorzolamide/timolol · 8.3
“Because of the potential for serious adverse reactions from dorzolamide hydrochloride and timolol maleate in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Dorzolamide/timolol · 8.4
“The safety and effectiveness of dorzolamide hydrochloride ophthalmic solution and timolol maleate ophthalmic solution have been established when administered individually in pediatric patients aged 2 years and older.”
- 👴 Older adultsNo specific problem stated
Label: no specific difference or dose adjustment stated for older adults. FDA Dorzolamide/timolol · 8.5
“No overall differences in safety or effectiveness have been observed between elderly and younger patients.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA207629
- DailyMed (FDA label)FDA Dorzolamide/timolol
- MedlinePlus (NIH)Dorzolamide Ophthalmic
- WHO ATC/DDDS01ED51
- Darooyab (Iran)Dorzolamide
🇮🇷 Registered in Iran Darooyab · G-1653/Dorzolamide
Dosage forms with Iranian generic codes, per Darooyab.
- 00469 · DORZOLAMIDE HCL 2% OPH DROP · قطره چشمی دورزولامید هیدروکلراید ۲ درصد
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Dorzolamide/timolol · 3FDA Dorzolamide/timolol · 2FDA Dorzolamide/timolol · 4FDA Dorzolamide/timolol · SPL approval / marketing categoryFDA Dorzolamide/timolol · 8.1FDA Dorzolamide/timolol · 8.3FDA Dorzolamide/timolol · 8.4FDA Dorzolamide/timolol · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1653/Dorzolamide
- Clinical review⚠ Unverified