Entecavir

🧮 Dose calculator

Chronic hepatitis B · Regimen source: FDA Baraclude · 2.2

• • On an empty stomach (2 h after a meal and 2 h before the next). CrCl <50: reduce per label Table 2. FDA Baraclude · 2.1FDA Baraclude · 2.4

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Baraclude · 8.1

  “Risk Summary Prospective pregnancy data from the APR are not sufficient to adequately assess the risk of birth defects, miscarriage or adverse maternal or fetal outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Baraclude · 8.2

  “When administered to lactating rats, entecavir was present in milk (see Data).”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Baraclude · 8.4

  “BARACLUDE was evaluated in two clinical trials of pediatric subjects 2 years of age and older with HBeAg-positive chronic HBV infection and compensated liver disease.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Baraclude · 8.5

  “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function [see Dosage and Administration (2.4) ].”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.