Dofetilide

🧮 Dose calculator

Atrial fibrillation / anticoagulation · Regimen source: FDA Tikosyn · Dosage and Administration

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Tikosyn · Pregnancy

  “Dofetilide has been shown to adversely affect in utero growth and survival of rats and mice when orally administered during organogenesis at doses of 2 or more mg/kg/day.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Tikosyn · Nursing Mothers

  “There is no information on the presence of dofetilide in breast milk.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Tikosyn · Pediatric Use

  “The safety and effectiveness of TIKOSYN in children (<18 years old) has not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Tikosyn · Geriatric Use

  “Because elderly patients are more likely to have decreased renal function with a reduced creatinine clearance, care must be taken in dose selection (see DOSAGE AND ADMINISTRATION ).”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.