Atazanavir
آتازاناویر
🦠 Antiinfectives For Systemic UseProtease inhibitor
Market / country: 🇺🇸 USA
Reyataz (US)
🧮 Dose calculator
HIV-1 infection (treatment) · Regimen source: FDA Reyataz · 2.3
- • Always with other antiretrovirals (unless a complete regimen). FDA Reyataz · 2.3
- • Treatment-naive alternative: 400 mg unboosted. Separate from H2 blockers/PPIs per label. Renal tests before and during therapy. FDA Reyataz · 2.3FDA Reyataz · 2.1FDA Reyataz · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Prior hypersensitivity (SJS, erythema multiforme); CYP3A/UGT1A1-dependent narrow-index drugs and strong inducers (per label table). FDA Reyataz · 4
Warnings
- • Cardiac conduction abnormalities (PR); rash; hyperbilirubinaemia; nephrolithiasis and cholelithiasis; chronic kidney disease. FDA Reyataz · 5
Formulations
- 300 mg capsule — capsule 🇺🇸 USA FDA Reyataz · 3
- 200 mg capsule — capsule 🇺🇸 USA FDA Reyataz · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Reyataz · 8.1
“Risk Summary Atazanavir has been evaluated in a limited number of women during pregnancy.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Reyataz · 8.2
“Risk Summary Atazanavir has been detected in human milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Reyataz · 8.4
“REYATAZ is indicated in combination with other antiretroviral agents for the treatment of pediatric patients with HIV-1, 3 months of age and older weighing at least 5 kg.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Reyataz · 8.5
“In general, appropriate caution should be exercised in the administration and monitoring of REYATAZ in elderly patients reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA021567
- DailyMed (FDA label)FDA Reyataz
- MedlinePlus (NIH)Atazanavir
- WHO ATC/DDDJ05AE08
- Darooyab (Iran)Atazanavir
🇮🇷 Registered in Iran Darooyab · G-1162/Atazanavir
Dosage forms with Iranian generic codes, per Darooyab.
- 18488 · ATAZANAVIR 150MG TAB. · قرص آتازاناویر ۱۵۰ میلیگرم .
- 12118 · ATAZANAVIR SULFATE 150MG CAP · کپسول آتازاناویر سولفات ۱۵۰ میلیگرم
- 53102 · ATAZANAVIR 200MG TAB · قرص آتازاناویر ۲۰۰ میلیگرم
- 52110 · ATAZANAVIR 200MG CAP · کپسول آتازاناویر ۲۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Reyataz · 3FDA Reyataz · 2.3FDA Reyataz · 2.1FDA Reyataz · 2FDA Reyataz · 4FDA Reyataz · 5FDA Reyataz · SPL approval / marketing categoryFDA Reyataz · 8.1FDA Reyataz · 8.2FDA Reyataz · 8.4FDA Reyataz · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1162/Atazanavir
- Clinical review⚠ Unverified