Zafirlukast

زافیرلوکاست

⚠ Unverified

🌬️ Respiratory SystemLeukotriene receptor antagonist

Market / country: 🇺🇸 USA

Accolate (US)

🧮 Dose calculator

Asthma and chronic lung disease (reversible airflow obstruction) · Regimen source: FDA Zafirlukast · Dosage and Administration

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🛡️ Safety & information

Contraindications

Warnings

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Zafirlukast · Precautions/Warnings – Pregnancy

    “Category B: No teratogenicity was observed at oral doses up to 1600 mg/kg/day in mice (approximately 160 times the maximum recommended daily oral dose in adults on a mg/m 2 basis), up to 2000 mg/kg/day in rats (approximately 410 times the maximum recommended daily oral dose in adults on a mg/m 2 basis) and up to 2000 …”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Zafirlukast · Precautions/Warnings – Nursing Mothers

    “Zafirlukast is excreted in breast milk.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Zafirlukast · Precautions/Warnings – Pediatric Use

    “The safety and effectiveness of zafirlukast for pediatric patients less than 5 years of age has not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Zafirlukast · Precautions/Warnings – Geriatric Use

    “Based on cross-study comparison, the clearance of zafirlukast is reduced in patients 65 years of age and older such that C max and AUC are approximately 2- to 3-fold greater than those of younger patients (see”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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