Omalizumab

🧮 Dose calculator

Chronic idiopathic urticaria · Regimen source: FDA Xolair · 2.5

• • One dose every 4 WEEKS (not daily); independent of IgE and weight. FDA Xolair · 2.5

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Xolair · 8.1

  “Risk Summary A registry study of XOLAIR exposure during pregnancy showed no increase in the rate of major birth defects or miscarriage.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Xolair · 8.2

  “Risk Summary There is no information regarding the presence of omalizumab in human milk, or the effects on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Xolair · 8.4

  “Asthma Safety and effectiveness of XOLAIR for moderate to severe persistent asthma who had a positive skin test or in vitro reactivity to a perennial aeroallergen and whose symptoms are inadequately controlled with inhaled corticosteroids, have been established in pediatric patients aged 6 years and older.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Xolair · 8.5

  “In clinical studies, 134 asthma patients, 20 CRSwNP patients, 37 CSU patients and no IgE-mediated food allergy patients 65 years of age or older were treated with XOLAIR.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.