Vinblastine
وینبلاستین
🎗️ Antineoplastic And Immunomodulating AgentsVinca alkaloid
Market / country: 🇺🇸 USA
Velban (US)
🧮 Dose calculator
Hodgkin lymphoma · Regimen source: FDA Vinblastine · Dosage and Administration
- • Only under an oncologist in an equipped centre. Calculator = label mg/m² × BSA (Mosteller); protocol, cycle interval and adjustment for CBC and renal/hepatic function rest with the oncology team. FDA Vinblastine · Dosage and Administration
- • Weekly increments by WBC: 5.5, 7.4, 9.25, 11.1 mg/m²; max 18.5 mg/m². IV only — intrathecal injection is fatal. FDA Vinblastine · Dosage and Administration
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Significant granulocytopenia (unless due to the disease treated); uncontrolled bacterial infection. FDA Vinblastine · Contraindications
Warnings
- • Boxed warning: IV only — fatal if given by other routes. Extravasation causes severe tissue injury. FDA Vinblastine · Boxed WarningFDA Vinblastine · Warnings
Formulations
- 1 mg/mL, 10 mL vial — injection 🇺🇸 USA FDA Vinblastine · How Supplied
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Vinblastine · Pregnancy Category D
“Vinblastine sulfate can cause fetal harm when administered to a pregnant woman.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Vinblastine · Nursing Mothers
“Because many drugs are excreted in human milk and because of the potential for serious adverse reactions from vinblastine sulfate in nursing infants, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the mother.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Vinblastine · Pediatric Use
“The dosage schedule for pediatric patients is indicated under DOSAGE AND ADMINISTRATION .”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA089515
- DailyMed (FDA label)FDA Vinblastine
- MedlinePlus (NIH)Vinblastine
- WHO ATC/DDDL01CA01
- Darooyab (Iran)Vinblastine
🇮🇷 Registered in Iran Darooyab · G-1090/Vinblastine
Dosage forms with Iranian generic codes, per Darooyab.
- 01283 · VINBLASTINE SULFATE 10MG VIAL · ویال وینبلاستین سولفات ۱۰ میلیگرم
- 12261 · VINBLASTINE SULFATE 5MG VIAL · ویال وینبلاستین سولفات ۵ میلیگرم
- 52631 · VINBLASTINE SULFATE INJECTION, SOLUTION PARENTERAL 1 mg/1mL 10 mL · محلول تزریقی وینبلاستین سولفات ۱ میلیگرم / ۱ میلیلیتر ۱۰ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Vinblastine · How SuppliedFDA Vinblastine · Dosage and AdministrationFDA Vinblastine · ContraindicationsFDA Vinblastine · Boxed WarningFDA Vinblastine · WarningsFDA Vinblastine · SPL approval / marketing categoryFDA Vinblastine · Pregnancy Category DFDA Vinblastine · Nursing MothersFDA Vinblastine · Pediatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1090/Vinblastine
- Clinical review⚠ Unverified