Tigecycline

🧮 Dose calculator

Complicated intra-abdominal infection and peritonitis · Regimen source: FDA Tygacil · 2.1

• • First dose 100 mg. Infuse over 30–60 min. Severe hepatic impairment: 100 then 25 mg every 12 h. Monitor fibrinogen and coagulation. FDA Tygacil · 2.1FDA Tygacil · 2.2FDA Tygacil · 2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Tygacil · 8.1

  “Risk Summary TYGACIL, like other tetracycline class antibacterial drugs, may cause permanent discoloration of deciduous teeth and reversible inhibition of bone growth when administered during the second and third trimesters of pregnancy [see Warnings and Precautions (5.7 , 5.8) , Data , and Use in Specific Populations …”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Tygacil · 8.2

  “Risk Summary There are no data on the presence of tigecycline in human milk; however, tetracycline-class antibacterial drugs are present in breast milk.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Tygacil · 8.4

  “Safety and effectiveness in pediatric patients below the age of 18 years have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Tygacil · 8.5

  “Of the total number of subjects who received TYGACIL in Phase 3 clinical studies (n=2514), 664 were 65 and over, while 288 were 75 and over.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.