Cefoxitin
سفوکسیتین
🦠 Antiinfectives For Systemic UseCephamycin (second-generation cephalosporin)
Market / country: 🇺🇸 USA
Mefoxin (US)
🧮 Dose calculator
Complicated intra-abdominal infection and peritonitis · Regimen source: FDA Cefoxitin · Dosage and Administration — Table 1
- • Moderate–severe: 1 g every 4 h or 2 g every 6–8 h (6–8 g/day); gas gangrene: up to 12 g/day. No activity against chlamydia. FDA Cefoxitin · Dosage and Administration — Table 1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to cefoxitin and cephalosporins. FDA Cefoxitin · Contraindications
Warnings
- • Serious hypersensitivity; Clostridioides difficile-associated diarrhoea. FDA Cefoxitin · Warnings
Renal adjustment
- • eGFR < 51: CrCl 30–50: 1–2 g every 8–12 h; lower per label Table 2. FDA Cefoxitin · Dosage and Administration — Table 2
Formulations
- 1 g vial — powder for injection 🇺🇸 USA FDA Cefoxitin · How Supplied
- 2 g vial — powder for injection 🇺🇸 USA FDA Cefoxitin · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Cefoxitin · Pregnancy
“Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Cefoxitin · Nursing Mothers
“Caution should be exercised when Cefoxitin for Injection is administered to a nursing woman.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Cefoxitin · Pediatric Use
“Safety and efficacy in pediatric patients from birth to 3 months of age have not yet been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Cefoxitin · Geriatric Use
“… should be taken in dose selection, and it may be useful to monitor renal function (see DOSAGE AND ADMINISTRATION and PRECAUTIONS).”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA065414
- DailyMed (FDA label)FDA Cefoxitin
- MedlinePlus (NIH)Cefoxitin Injection
- WHO ATC/DDDJ01DC01
- Darooyab (Iran)Cefoxitin
🇮🇷 Not found in Iran list Darooyab · G-338/Cefoxitin
Darooyab lists no registered dosage form or brand for this drug. This does not prove it is unavailable.
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Cefoxitin · How SuppliedFDA Cefoxitin · Dosage and Administration — Table 1FDA Cefoxitin · Dosage and AdministrationFDA Cefoxitin · ContraindicationsFDA Cefoxitin · WarningsFDA Cefoxitin · Dosage and Administration — Table 2FDA Cefoxitin · PregnancyFDA Cefoxitin · Nursing MothersFDA Cefoxitin · Pediatric UseFDA Cefoxitin · Geriatric UseFDA Cefoxitin · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-338/Cefoxitin
- Clinical review⚠ Unverified