Sildenafil

🧮 Dose calculator

Erectile dysfunction · Regimen source: FDA Sildenafil · 2.1

• • 25–100 mg; at most once daily; 30 min to 4 h before. Over 65, hepatic impairment or CrCl <30: start 25 mg. With ritonavir max 25 mg per 48 h. FDA Sildenafil · 2FDA Sildenafil · 2.5FDA Sildenafil · 2.4

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Sildenafil · 8.1

  “Risk Summary Sildenafil is not indicated for use in females.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Sildenafil · 8.2

  “Risk Summary Sildenafil is not indicated for use in females.”

• 👶 ChildrenUse with caution

  Revatio label: approved for PAH in children 1–17 years; erectile-dysfunction use does not apply to children. FDA Revatio · 8.4

  “The safety and efficacy of REVATIO have been established in pediatric patients 1 to 17 years old, for the treatment of PAH (WHO Group I) to improve exercise ability and, in patients too young to perform standard exercising testing, pulmonary hemodynamics thought to underlie improvements in exercise.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Sildenafil · 8.5

  “Healthy elderly volunteers (65 years or over) had a reduced clearance of sildenafil resulting in approximately 84% and 107% higher plasma AUC values of sildenafil and its active N-desmethyl metabolite, respectively, compared to those seen in healthy young volunteers (18-45 years) [ see Clinical Pharmacology (12.3) ].”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.