Romiplostim

🧮 Dose calculator

Immune thrombocytopenia (ITP) · Regimen source: FDA Nplate · 2.1

• • Increase weekly by 1 mcg/kg until platelets ≥50×10⁹/L; max 10 mcg/kg/week; use actual body weight at initiation. Syringe with 0.01 mL graduations. Stop if no response after 4 weeks at max dose. FDA Nplate · 2.1FDA Nplate · 2.3

Enter age and weight.

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Nplate · 8.1

  “Risk Summary Based on findings from animal reproduction studies, Nplate may cause fetal harm when administered to a pregnant woman.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Nplate · 8.2

  “Due to the potential for serious adverse reactions in a breastfed child from Nplate, advise women not to breastfeed during treatment with Nplate.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Nplate · 8.4

  “Safety and effectiveness of Nplate have been established in pediatric patients age 1 year and older with ITP for at least 6 months evaluated in two randomized, placebo-controlled studies.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Nplate · 8.5

  “In general, dose adjustment for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.