Riluzole

🧮 Dose calculator

Amyotrophic lateral sclerosis (ALS) · Regimen source: FDA Riluzole · 2

• • Check aminotransferases before and during treatment. FDA Riluzole · 2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Riluzole · 8.1

  “Risk Summary There are no studies of riluzole in pregnant women, and case reports have been inadequate to inform the drug-associated risk.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Riluzole · 8.2

  “Risk Summary It is not known if riluzole is excreted in human milk.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Riluzole · 8.4

  “Safety and effectiveness of riluzole tablets in pediatric patients have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Riluzole · 8.5

  “In clinical studies of riluzole tablets, 30% of patients were 65 years and over.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Riluzole · 8.3

  “In rats, oral administration of riluzole resulted in decreased fertility indices and increases in embryolethality [see Nonclinical Toxicology (13.1)].”