Doz

Amyotrophic lateral sclerosis (ALS)

Amyotrophic lateral sclerosis (ALS) · ICD-10: G12.21

Symptoms

  • • Muscle weakness starting in one limb and slowly worsening
  • • Difficulty climbing stairs, walking and getting up
  • • Difficulty swallowing, drooling, choking
  • • Slow or slurred speech, hoarseness
  • • Breathing difficulty
  • • Muscle twitching (fasciculations), cramps and stiffness
  • • Head drop from neck weakness; weight loss
  • • Senses intact; thinking usually normal

MedlinePlus · Symptoms

Drugs and regimens

Edaravone⚠ Unverified

ALS — cycles: 60 mg IV or 105 mg oral daily for 14 days, 14 days off; then 10 of 14 days

Riluzole⚠ Unverified

ALS — 50 mg twice daily, 1 h before or 2 h after a meal

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