Ranolazine
رانولازین
❤️ Cardiovascular SystemAntianginal
Market / country: 🇺🇸 USA
Ranexa (US)
🧮 Dose calculator
Angina pectoris · Regimen source: FDA Ranolazine ER · 2.1
- • Swallow whole (do not crush, break or chew). Lower maximum with some drugs (section 7). FDA Ranolazine ER · 2.1FDA Ranolazine ER · 2.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Strong CYP3A inhibitors (ketoconazole, clarithromycin); CYP3A inducers (rifampin, phenobarbital, St John’s wort); liver cirrhosis. FDA Ranolazine ER · 4
Formulations
- 500 mg extended-release tablet — tablet 🇺🇸 USA FDA Ranolazine ER · 3
- 1000 mg extended-release tablet — tablet 🇺🇸 USA FDA Ranolazine ER · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Ranolazine ER · 8.1
“Risk Summary There are no available data on ranolazine use in pregnant women to inform any drug-associated risks.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Ranolazine ER · 8.2
“Risk Summary There are no data on the presence of ranolazine in human milk, the effects on the breastfed infant, or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Ranolazine ER · 8.4
“Safety and effectiveness have not been established in pediatric patients.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Ranolazine ER · 8.5
“In general, dose selection for an elderly patient should usually start at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease, or other drug therapy.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA210188
- DailyMed (FDA label)FDA Ranolazine ER
- MedlinePlus (NIH)Ranolazine
- WHO ATC/DDDC01EB18
- Darooyab (Iran)Ranolazine
🇮🇷 Registered in Iran Darooyab · G-1866/Ranolazine
Dosage forms with Iranian generic codes, per Darooyab.
- 13980 · RANOLASINE 500MG TAB · قرص رانولاسین ۵۰۰ میلیگرم
- 21152 · RANOLASINE 750MG TAB · قرص رانولاسین ۷۵۰ میلیگرم
- 53016 · RANOLASINE 1000MG TAB · قرص رانولاسین ۱۰۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Ranolazine ER · 3FDA Ranolazine ER · 2.1FDA Ranolazine ER · 2.2FDA Ranolazine ER · 4FDA Ranolazine ER · 8.1FDA Ranolazine ER · 8.2FDA Ranolazine ER · 8.4FDA Ranolazine ER · 8.5FDA Ranolazine ER · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1866/Ranolazine
- Clinical review⚠ Unverified