Ranolazine

رانولازین

⚠ Unverified

❤️ Cardiovascular SystemAntianginal

Market / country: 🇺🇸 USA

Ranexa (US)

🧮 Dose calculator

Angina pectoris · Regimen source: FDA Ranolazine ER · 2.1

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🛡️ Safety & information

Contraindications

  • ⛔ Strong CYP3A inhibitors (ketoconazole, clarithromycin); CYP3A inducers (rifampin, phenobarbital, St John’s wort); liver cirrhosis. FDA Ranolazine ER · 4

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Ranolazine ER · 8.1

    “Risk Summary There are no available data on ranolazine use in pregnant women to inform any drug-associated risks.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Ranolazine ER · 8.2

    “Risk Summary There are no data on the presence of ranolazine in human milk, the effects on the breastfed infant, or the effects on milk production.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Ranolazine ER · 8.4

    “Safety and effectiveness have not been established in pediatric patients.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Ranolazine ER · 8.5

    “In general, dose selection for an elderly patient should usually start at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease, or other drug therapy.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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