Isosorbide mononitrate
ایزوسورباید مونونیترات
❤️ Cardiovascular SystemNitrate
Market / country: 🇺🇸 USA
Monoket (US)
🧮 Dose calculator
Angina pectoris · Regimen source: FDA ISMN (Genus) · Dosage and Administration
- • The 7-h gap prevents nitrate tolerance. Small stature: start 5 mg, increase to at least 10 mg by day 2–3. FDA ISMN (Genus) · Dosage and Administration
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Allergy to isosorbide mononitrate. FDA ISMN (Genus) · Contraindications
Important interactions
- • With sildenafil, tadalafil, vardenafil and other PDE5 inhibitors: severe hypotension. FDA ISMN (Genus) · Precautions — Drug InteractionsFDA Verapamil ER · Contraindications
Formulations
- 10 mg tablet (scored) — tablet 🇺🇸 USA FDA ISMN (Genus) · How Supplied
- 20 mg tablet (scored) — tablet 🇺🇸 USA FDA ISMN (Genus) · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA ISMN (Genus) · Pregnancy
“Because animal reproduction studies are not always predictive of human response, isosorbide mononitrate should be used during pregnancy only if clearly needed.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA ISMN (Genus) · Nursing Mothers
“Because many drugs are excreted in human milk, caution should be exercised when isosorbide mononitrate is administered to a nursing woman.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA ISMN (Genus) · Pediatric Use
“Safety and effectiveness of isosorbide mononitrate in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA ISMN (Genus) · Geriatric Use
“In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA075037
- DailyMed (FDA label)FDA ISMN (Genus)FDA Verapamil ER
- MedlinePlus (NIH)Isosorbide
- WHO ATC/DDDC01DA14
- Darooyab (Iran)Isosorbide-Mononitrate
🇮🇷 Registered in Iran Darooyab · G-1722/Isosorbide-Mononitrate
Dosage forms with Iranian generic codes, per Darooyab.
- 19061 · ISOSORBIDE MONONITRAT 10MG TAB · قرص ایزوسورباید مونونیترات ۱۰ میلیگرم
- 19060 · ISOSORBIDE MONONITRAT 20MG TAB · قرص ایزوسورباید مونونیترات ۲۰ میلیگرم
- 19064 · ISOSORBIDE MONONITRAT 40MG TAB · قرص ایزوسورباید مونونیترات ۴۰ میلیگرم
- 10014 · ISOSORBIDE MONONITRATE SR 50MG CAP · کپسول آهستهرهش ایزوسورباید مونونیترات ۵۰ میلیگرم
- 01560 · ISOSORBIDE MONONITRATE SR 60MG TAB · قرص آهستهرهش ایزوسورباید مونونیترات ۶۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA ISMN (Genus) · How SuppliedFDA ISMN (Genus) · Dosage and AdministrationFDA ISMN (Genus) · ContraindicationsFDA ISMN (Genus) · Precautions — Drug InteractionsFDA Verapamil ER · ContraindicationsFDA ISMN (Genus) · PregnancyFDA ISMN (Genus) · Nursing MothersFDA ISMN (Genus) · Pediatric UseFDA ISMN (Genus) · Geriatric UseFDA ISMN (Genus) · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1722/Isosorbide-Mononitrate
- Clinical review⚠ Unverified