Paricalcitol

پاری‌کلسیتول

⚠ Unverified

🧬 Systemic Hormonal Preparations, Excl. Sex Hormones And InsulinsActive vitamin D analogue

Market / country: 🇺🇸 USA

Zemplar (US)

🧮 Dose calculator

Secondary hyperparathyroidism in chronic kidney disease · Regimen source: FDA Zemplar injection · 2.2

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🛡️ Safety & information

Contraindications

Warnings

  • • Hypercalcaemia; digitalis toxicity potentiated by hypercalcaemia; adynamic bone disease with PTH over-suppression. FDA Zemplar injection · 5

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Zemplar injection · 8.1

    “Risk Summary Limited data with ZEMPLAR in pregnant women are insufficient to inform a drug-associated risk for major birth defects and miscarriage.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Zemplar injection · 8.2

    “Risk Summary There is no information available on the presence of paricalcitol in human milk, the effects of the drug on the breastfed infant or the effects of the drug on milk production.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Zemplar injection · 8.4

    “The safety and efficacy of ZEMPLAR for the prevention and treatment of secondary hyperparathyroidism associated with CKD have been established in pediatric patients 5 years of age and older with CKD on dialysis.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Zemplar injection · 8.5

    “In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic or cardiac function, and of concomitant disease or other drug therapy.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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