Cinacalcet
سیناکلست
🧬 Systemic Hormonal Preparations, Excl. Sex Hormones And InsulinsCalcimimetic
Market / country: 🇺🇸 USA
Sensipar (US)
🧮 Dose calculator
Secondary hyperparathyroidism in chronic kidney disease · Regimen source: FDA Sensipar · 2.2
- • Every 2–4 weeks: 30 → 60 → 90 → 120 → 180 mg to iPTH 150–300. Calcium and phosphorus within 1 week, iPTH 1–4 weeks after each change. With food; swallow whole. FDA Sensipar · 2.2FDA Sensipar · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Starting treatment when serum calcium is below normal. FDA Sensipar · 4
Formulations
- 30 mg tablet — tablet 🇺🇸 USA FDA Sensipar · 3
- 60 mg tablet — tablet 🇺🇸 USA FDA Sensipar · 3
- 90 mg tablet — tablet 🇺🇸 USA FDA Sensipar · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Sensipar · 8.1
“Risk Summary Limited case reports of Sensipar use in pregnant women are insufficient to inform a drug associated risk of adverse developmental outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Sensipar · 8.2
“Risk Summary There are no data regarding the presence of Sensipar in human milk or effects on the breastfed infant or on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Sensipar · 8.4
“The safety and efficacy of Sensipar have not been established in pediatric patients.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Sensipar · 8.5
“Of the total number of subjects (n = 1136) in clinical studies of Sensipar, 26 percent were 65 and over, and 9 percent were 75 and over.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA021688
- DailyMed (FDA label)FDA Sensipar
- MedlinePlus (NIH)Cinacalcet
- WHO ATC/DDDH05BX01
- Darooyab (Iran)Cinacalcet
🇮🇷 Registered in Iran Darooyab · G-1431/Cinacalcet
Dosage forms with Iranian generic codes, per Darooyab.
- 08066 · CINACALCET 30MG TAB · قرص سیناکالست ۳۰ میلیگرم
- 13571 · CINACALCET 60MG TAB · قرص سیناکالست ۶۰ میلیگرم
- 13610 · CINACALCET 90MG TAB · قرص سیناکالست ۹۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Sensipar · 3FDA Sensipar · 2.2FDA Sensipar · 2.1FDA Sensipar · 4FDA Sensipar · 8.1FDA Sensipar · 8.2FDA Sensipar · 8.4FDA Sensipar · 8.5FDA Sensipar · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1431/Cinacalcet
- Clinical review⚠ Unverified