Modafinil
مودافینیل
🧠 Nervous SystemWakefulness-promoting agent
Market / country: 🇺🇸 USA
Provigil (US)
🧮 Dose calculator
Narcolepsy and excessive daytime sleepiness · Regimen source: FDA Modafinil · 2.1
- • Up to 400 mg tolerated but no consistent extra benefit. Severe hepatic impairment: half dose. Elderly: consider lower dose. FDA Modafinil · 2.1FDA Modafinil · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to modafinil or armodafinil. FDA Modafinil · 4
Warnings
- • Serious rash (SJS) — stop at the first rash; angioedema and anaphylaxis; multi-organ hypersensitivity; persistent sleepiness; psychiatric symptoms. FDA Modafinil · 5
Formulations
- 100 mg tablet — tablet 🇺🇸 USA FDA Modafinil · 3
- 200 mg tablet (scored) — tablet 🇺🇸 USA FDA Modafinil · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Modafinil · 8.1
“Pregnancy Category C There are no adequate and well-controlled studies of modafinil in pregnant women.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Modafinil · 8.3
“Because many drugs are excreted in human milk, caution should be exercised when modafinil tablets are administered to a nursing woman.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Modafinil · 8.4
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Modafinil · 8.5
“Therefore, consideration should be given to the use of lower doses and close monitoring in this population [see Dosage and Administration (2.4) and Clinical Pharmacology (12.3)].”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA207196
- DailyMed (FDA label)FDA Modafinil
- MedlinePlus (NIH)Modafinil
- WHO ATC/DDDN06BA07
- Darooyab (Iran)Modafinil
🇮🇷 Registered in Iran Darooyab · G-3393/Modafinil
Dosage forms with Iranian generic codes, per Darooyab.
- 06579 · MODAFINIL 100MG TAB · قرص مودافینیل ۱۰۰ میلیگرم
- 08504 · MODAFINIL 200MG TAB · قرص مودافینیل ۲۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Modafinil · 3FDA Modafinil · 2.1FDA Modafinil · 2FDA Modafinil · 2.2FDA Modafinil · 4FDA Modafinil · 5FDA Modafinil · SPL approval / marketing categoryFDA Modafinil · 8.1FDA Modafinil · 8.3FDA Modafinil · 8.4FDA Modafinil · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-3393/Modafinil
- Clinical review⚠ Unverified