Mexiletine

🧮 Dose calculator

Life-threatening ventricular arrhythmia · Regimen source: FDA Mexiletine · Dosage and Administration

• • Most are controlled by 200–300 mg every 8 h; adjust by 50 or 100 mg every 2–3 days. Rapid control: 400 mg loading then 200 mg 8 h later. ECG and Holter monitoring. FDA Mexiletine · Dosage and Administration

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Mexiletine · Precautions/Warnings – Pregnancy

  “Teratogenic Effects Reproduction studies performed with mexiletine in rats, mice and rabbits at doses up to four times the maximum human oral dose (24 mg/kg in a 50 kg patient) revealed no evidence of teratogenicity or impaired fertility but did show an increase in fetal resorption.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Mexiletine · Precautions/Warnings – Nursing Mothers

  “Mexiletine appears in human milk in concentrations similar to those observed in plasma.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Mexiletine · Precautions/Warnings – Pediatric Use

  “Safety and effectiveness in pediatric patients have not been established.”

• 👴 Older adultsNo data

  The source for this drug has no section for this group.

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.