Domperidone

دومپریدون

⚠ Unverified

🩺 GastrointestinalDopamine antagonist; antiemetic

Market / country: 🇬🇧 UK

Motilium (GB)

🧮 Dose calculator

Nausea and vomiting · Regimen source: UK SmPC Domperidone · 4.2

  • • Lowest effective dose for the shortest duration; usually no more than one week. 15–30 min before meals. UK SmPC Domperidone · 4.2

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🛡️ Safety & information

Contraindications

  • ⛔ Known QTc prolongation, significant electrolyte disturbance or underlying cardiac disease; with QT-prolonging drugs or potent CYP3A4 inhibitors. UK SmPC Domperidone · 4.3
  • ⛔ Prolactinoma; phaeochromocytoma; GI haemorrhage, obstruction or perforation; moderate or severe hepatic impairment. UK SmPC Domperidone · 4.3

Warnings

  • • QT prolongation, serious ventricular arrhythmia and sudden cardiac death; higher risk over 60 years and above 30 mg/day. UK SmPC Domperidone · 4.4

Formulations

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