Linaclotide

🧮 Dose calculator

Functional bowel / irritable bowel syndrome · Regimen source: FDA Linzess · 2.1

• • On an empty stomach at least 30 min before a meal; do not crush or chew. FDA Linzess · 2.1FDA Linzess · 2.2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Darooyab: category C — only if benefit outweighs risk. Darooyab · G-5499/Linaclotide — مصرف در بارداری

  “مصرف در بارداری لیناکلوتاید گروه C در شرايط خاص و نظارت ويژه پزشك قابل استفاده است:”

• 🤱 BreastfeedingNo specific problem stated

  Label: infant exposure not expected. FDA Linzess · 8.2

  “Maternal use of LINZESS is not expected to result in exposure to linaclotide or its active metabolite in breastfed infants.”

• 👶 ChildrenUse with caution

  Label: contraindicated under 2 years (serious dehydration); approved for functional constipation from 2 y and IBS-C from 7 y. FDA Linzess · 4

  “LINZESS is contraindicated in: Patients less than 2 years of age due to the risk of serious dehydration”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Linzess · 8.5

  “In general, dose selection for an elderly patient should be cautious reflecting the greater frequency of decreased hepatic, renal or cardiac function and of concomitant disease or other drug therapy.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.