Ixekizumab
ایکسکیزوماب
🎗️ Antineoplastic And Immunomodulating AgentsAnti-IL-17A antibody
Market / country: 🇺🇸 USA
Taltz (US)
🧮 Dose calculator
Psoriasis and steroid-responsive dermatoses · Regimen source: FDA Taltz · 2.2
- • Before starting: screen for active and latent TB (treat latent TB first) and complete age-appropriate vaccines. FDA Taltz · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Serious hypersensitivity to ixekizumab. FDA Taltz · 4
Warnings
- • Infections; TB (screen first); hypersensitivity; eczematous eruptions; inflammatory bowel disease (new or worse); no live vaccines. FDA Taltz · 5
Formulations
- 80 mg/mL autoinjector or syringe — injection 🇺🇸 USA FDA Taltz · 3
- 40 mg/0.5 mL syringe — injection 🇺🇸 USA FDA Taltz · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Taltz · 8.1
“Risk Summary Available data from the published literature and the pharmacovigilance database with TALTZ use in pregnant women are insufficient to evaluate for a drug-associated risk of major birth defects, miscarriage or other adverse maternal or fetal outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Taltz · 8.2
“Risk Summary There are no available data on the presence of ixekizumab in human milk, the effects on the breastfed infant, or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Taltz · 8.4
“The safety and effectiveness of TALTZ have been established in pediatric subjects aged 6 years to less than 18 years with moderate-to-severe plaque psoriasis.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Taltz · 8.5
“Of the 4204 adult psoriasis subjects exposed to TALTZ, a total of 301 were 65 years or older, and 36 subjects were 75 years or older.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)BLA125521
- DailyMed (FDA label)FDA Taltz
- MedlinePlus (NIH)Ixekizumab Injection
- WHO ATC/DDDL04AC13
- Darooyab (Iran)❌ None
🇮🇷 Not found in Iran list Darooyab · search
Darooyab lists no registered dosage form or brand for this drug. This does not prove it is unavailable.
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Taltz · 3FDA Taltz · 2.2FDA Taltz · 2.1FDA Taltz · 2.3, Table 1FDA Taltz · 2.4FDA Taltz · 2.5FDA Taltz · 2.6FDA Taltz · 4FDA Taltz · 5FDA Taltz · SPL approval / marketing categoryFDA Taltz · 8.1FDA Taltz · 8.2FDA Taltz · 8.4FDA Taltz · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · search
- Clinical review⚠ Unverified