Ethacrynic acid
اتاکرینیک اسید
❤️ Cardiovascular SystemLoop diuretic (non-sulfonamide)
Market / country: 🇺🇸 USA
Edecrin (US)
🧮 Dose calculator
Edema · Regimen source: FDA Edecrin · Dosage and Administration
- • Adjust in 25–50 mg steps; weigh daily. Day 2: 50 mg twice; day 3: 100 mg morning and 50–100 mg evening if needed. Option in sulfonamide allergy. FDA Edecrin · Dosage and Administration
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Anuria; infants; prior severe watery diarrhoea with the drug; hypersensitivity. FDA Edecrin · Contraindications
Warnings
- • Profound diuresis and dehydration, electrolyte loss (hypokalaemia); ototoxicity especially IV or with aminoglycosides. FDA Edecrin · Warnings
Formulations
- 25 mg tablet (scored) — tablet 🇺🇸 USA FDA Edecrin · How Supplied
- Sodium Edecrin 50 mg vial — powder for injection 🇺🇸 USA FDA Edecrin · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Edecrin · Pregnancy
“Since animal reproduction studies are not always predictive of human response, EDECRIN should be used during pregnancy only if clearly needed.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Edecrin · Nursing Mothers
“Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from EDECRIN, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.”
- 👶 ChildrenUse with caution
Label: oral use in children (not infants) supported by empiric use; infants and IV use in children not established. FDA Edecrin · Pediatric Use
“The information on oral dosing in pediatric patients, other than infants, is supported by evidence from empiric use in this age group.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Edecrin · Geriatric Use
“Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA016092
- DailyMed (FDA label)FDA Edecrin
- MedlinePlus (NIH)Ethacrynic Acid
- WHO ATC/DDDC03CC01
- Darooyab (Iran)Etacrynic-Acid
🇮🇷 Registered in Iran Darooyab · G-1669/Etacrynic-Acid
Dosage forms with Iranian generic codes, per Darooyab.
- 00506 · ETHACRIDINE LACTATE_RIVANOL_BULK · ماده اولیه اتاکریدین لاکتات ریوانول
- 00507 · ETHACRYNIC ACID 50MG TAB · قرص اتاکرینیک اسید ۵۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Edecrin · How SuppliedFDA Edecrin · Dosage and AdministrationFDA Edecrin · ContraindicationsFDA Edecrin · WarningsFDA Edecrin · PregnancyFDA Edecrin · Nursing MothersFDA Edecrin · Pediatric UseFDA Edecrin · Geriatric UseFDA Edecrin · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1669/Etacrynic-Acid
- Clinical review⚠ Unverified