Ertapenem

ارتاپنم

⚠ Unverified

🦠 Antiinfectives For Systemic UseCarbapenem

Market / country: 🇺🇸 USA

Invanz (US)

🧮 Dose calculator

Diabetic foot infection · Regimen source: FDA Ertapenem · 2.2, Table 1

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Hypersensitivity to any component or other carbapenems; anaphylaxis with beta-lactams. IM (lidocaine diluent): hypersensitivity to amide local anaesthetics. FDA Ertapenem · 4

Warnings

  • • Serious hypersensitivity; seizures and CNS effects; C. difficile diarrhoea. Lowers valproate levels with breakthrough seizure risk. FDA Ertapenem · 5

Important interactions

  • • Valproic acid and divalproex: reduced valproate levels and seizures. FDA Ertapenem · 5

Renal adjustment

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Ertapenem · 8.1

    “Risk Summary Available data from a small number of post-marketing cases with Ertapenem for injection use in pregnancy are insufficient to inform any drug-associated risks for major birth defects, miscarriage, or adverse maternal or fetal outcomes.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Ertapenem · 8.2

    “Risk Summary Ertapenem is present in human milk (see Data ).”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Ertapenem · 8.4

    “Safety and effectiveness of Ertapenem for injection in pediatric patients 3 months to 17 years of age are supported by evidence from adequate and well-controlled trials in adults, pharmacokinetic data in pediatric patients, and additional data from comparator-controlled trials in pediatric patients 3 months to 17 …”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Ertapenem · 8.5

    “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function [see Dosage and Administration (2.2) ].”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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