Ertapenem
ارتاپنم
🦠 Antiinfectives For Systemic UseCarbapenem
Market / country: 🇺🇸 USA
Invanz (US)
🧮 Dose calculator
Diabetic foot infection · Regimen source: FDA Ertapenem · 2.2, Table 1
- • Not studied in diabetic foot infection with concomitant osteomyelitis. Infuse over 30 min; no dextrose diluents. FDA Ertapenem · 2.2, Table 1FDA Ertapenem · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to any component or other carbapenems; anaphylaxis with beta-lactams. IM (lidocaine diluent): hypersensitivity to amide local anaesthetics. FDA Ertapenem · 4
Warnings
- • Serious hypersensitivity; seizures and CNS effects; C. difficile diarrhoea. Lowers valproate levels with breakthrough seizure risk. FDA Ertapenem · 5
Important interactions
- • Valproic acid and divalproex: reduced valproate levels and seizures. FDA Ertapenem · 5
Renal adjustment
- • eGFR < 31: CrCl ≤30 (and ESRD): 500 mg daily. Haemodialysis: give 150 mg after dialysis if the daily dose was given within 6 h before. FDA Ertapenem · 2.4FDA Ertapenem · 2.5
Formulations
- 1 g vial (IV or IM) — powder for injection 🇺🇸 USA FDA Ertapenem · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Ertapenem · 8.1
“Risk Summary Available data from a small number of post-marketing cases with Ertapenem for injection use in pregnancy are insufficient to inform any drug-associated risks for major birth defects, miscarriage, or adverse maternal or fetal outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Ertapenem · 8.2
“Risk Summary Ertapenem is present in human milk (see Data ).”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Ertapenem · 8.4
“Safety and effectiveness of Ertapenem for injection in pediatric patients 3 months to 17 years of age are supported by evidence from adequate and well-controlled trials in adults, pharmacokinetic data in pediatric patients, and additional data from comparator-controlled trials in pediatric patients 3 months to 17 …”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Ertapenem · 8.5
“Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function [see Dosage and Administration (2.2) ].”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA207647
- DailyMed (FDA label)FDA Ertapenem
- MedlinePlus (NIH)Ertapenem Injection
- WHO ATC/DDDJ01DH03
- Darooyab (Iran)Ertapenem
🇮🇷 Not found in Iran list Darooyab · G-389/Ertapenem
Darooyab lists no registered dosage form or brand for this drug. This does not prove it is unavailable.
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Ertapenem · 3FDA Ertapenem · 2.2, Table 1FDA Ertapenem · 2.1FDA Ertapenem · 2.2FDA Ertapenem · 2.3FDA Ertapenem · 4FDA Ertapenem · 5FDA Ertapenem · 2.4FDA Ertapenem · 2.5FDA Ertapenem · SPL approval / marketing categoryFDA Ertapenem · 8.1FDA Ertapenem · 8.2FDA Ertapenem · 8.4FDA Ertapenem · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-389/Ertapenem
- Clinical review⚠ Unverified