Edetate calcium disodium (CaNa2EDTA)
ادتات کلسیم دیسدیم (CaNa2EDTA)
🧪 VariousLead chelator
Market / country: 🇺🇸 USA
Calcium Disodium Versenate (US)
🧮 Dose calculator
Heavy-metal poisoning (lead, arsenic, mercury, gold) · Regimen source: FDA Edetate Ca disodium · Dosage and Administration
- • Remove the lead source first. Lead encephalopathy with cerebral oedema: IM preferred (fatal ICP rise with IV infusion). FDA Edetate Ca disodium · Dosage and AdministrationFDA Edetate Ca disodium · Boxed Warning
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Anuria; active renal disease or hepatitis. FDA Edetate Ca disodium · Contraindications
Warnings
- • Boxed warning: potentially fatal toxicity; fatal ICP rise with rapid IV infusion in lead encephalopathy. Do not confuse with edetate disodium (calcium-free). FDA Edetate Ca disodium · Boxed Warning
Formulations
- 200 mg/mL, 5 mL vial (1 g) — injection 🇺🇸 USA FDA Edetate Ca disodium · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Edetate Ca disodium · Pregnancy
“Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Edetate Ca disodium · Nursing Mothers
“Because many drugs are excreted in human milk, caution should be exercised when edetate calcium disodium is administered to a nursing woman.”
- 👶 ChildrenUse with caution
Label: lead encephalopathy is more common and lethal in children; with cerebral oedema the IM route is preferred and rapid IV infusion avoided. FDA Edetate Ca disodium · Boxed Warning
“Lead encephalopathy is relatively rare in adults, but occurs more often in pediatric patients in whom it may be incipient and thus overlooked. The mortality rate in pediatric patients has been high. Patients with lead encephalopathy and cerebral edema may experience a lethal increase in intracranial pressure following intravenous infusion; the intramuscular route is preferred for these patients.”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA216435
- DailyMed (FDA label)FDA Edetate Ca disodium
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDV03AB03
- Darooyab (Iran)Calcium-Disodium-Edetate
🇮🇷 Registered in Iran Darooyab · G-1979/Calcium-Disodium-Edetate
Dosage forms with Iranian generic codes, per Darooyab.
- 00480 · EDETATE CALCIUM DISODIUM 1.9G/10ML AMP · آمپول ادتات کلسیم دیسدیم ۱٫۹ گرم / ۱۰ میلیلیتر
- 01485 · EDETATE CALCIUM DISODIUM 50MG/ML AMP · آمپول ادتات کلسیم دیسدیم ۵۰ میلیگرم / میلیلیتر
- 50075 · EDETATE CALCIUM DISODIUM INJECTION PARENTERAL 200 mg/1mL 5 mL · فرآورده تزریقی ادتات کلسیم دیسدیم ۲۰۰ میلیگرم / ۱ میلیلیتر ۵ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Edetate Ca disodium · How SuppliedFDA Edetate Ca disodium · Dosage and AdministrationFDA Edetate Ca disodium · Boxed WarningFDA Edetate Ca disodium · ContraindicationsFDA Edetate Ca disodium · PregnancyFDA Edetate Ca disodium · Nursing MothersFDA Edetate Ca disodium · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1979/Calcium-Disodium-Edetate
- Clinical review⚠ Unverified