Edetate calcium disodium (CaNa2EDTA)

ادتات کلسیم دی‌سدیم (CaNa2EDTA)

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🧪 VariousLead chelator

Market / country: 🇺🇸 USA

Calcium Disodium Versenate (US)

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Heavy-metal poisoning (lead, arsenic, mercury, gold) · Regimen source: FDA Edetate Ca disodium · Dosage and Administration

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🛡️ Safety & information

Contraindications

Warnings

  • • Boxed warning: potentially fatal toxicity; fatal ICP rise with rapid IV infusion in lead encephalopathy. Do not confuse with edetate disodium (calcium-free). FDA Edetate Ca disodium · Boxed Warning

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Edetate Ca disodium · Pregnancy

    “Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Edetate Ca disodium · Nursing Mothers

    “Because many drugs are excreted in human milk, caution should be exercised when edetate calcium disodium is administered to a nursing woman.”
  • 👶 ChildrenUse with caution

    Label: lead encephalopathy is more common and lethal in children; with cerebral oedema the IM route is preferred and rapid IV infusion avoided. FDA Edetate Ca disodium · Boxed Warning

    “Lead encephalopathy is relatively rare in adults, but occurs more often in pediatric patients in whom it may be incipient and thus overlooked. The mortality rate in pediatric patients has been high. Patients with lead encephalopathy and cerebral edema may experience a lethal increase in intracranial pressure following intravenous infusion; the intramuscular route is preferred for these patients.”
  • 👴 Older adultsNo data

    The source for this drug has no section for this group.

  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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