Succimer (DMSA)
سوکسیمر (DMSA)
🧪 VariousOral lead chelator
Market / country: 🇺🇸 USA
Chemet (US)
🧮 Dose calculator
Heavy-metal poisoning (lead, arsenic, mercury, gold) · Regimen source: FDA Chemet · 2.2
- • Or 350 mg/m². Total course 19 days. Remove the lead source first; CBC, ANC >1500 and transaminases. Keep well hydrated. FDA Chemet · 2.2FDA Chemet · 2.1FDA Chemet · 2.3
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ History of hypersensitivity to succimer. FDA Chemet · 4
Warnings
- • Skin and hypersensitivity reactions; neutropenia; hepatotoxicity; embryo-fetal toxicity. FDA Chemet · 5
Formulations
- 100 mg capsule (may be sprinkled on food) — capsule 🇺🇸 USA FDA Chemet · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Chemet · 8.1
“Risk Summary There are no studies with the use of CHEMET in pregnant women to inform drug-associated risks.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Chemet · 8.2
“Risk Summary There are no data on the presence of succimer or its metabolite in either human or animal milk, the effects on the breastfed infant, or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Chemet · 8.4
“The safety and effectiveness of CHEMET for the treatment of lead poisoning in patients with blood levels above 45 mcg/mL have been established in pediatric patients aged 1 year and older.”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Chemet · 8.3
“Contraception Females Advise females of reproductive potential to use effective contraception during treatment with CHEMET and for 14 days after the final dose.”
🔗 Reference links
- FDA (approval record)NDA019998
- DailyMed (FDA label)FDA Chemet
- MedlinePlus (NIH)❌ None
- WHO ATC/DDD❌ None
- Darooyab (Iran)Succimer
🇮🇷 Registered in Iran Darooyab · G-1985/Succimer
Dosage forms with Iranian generic codes, per Darooyab.
- 02400 · SUCCIMER 100MG CAP · کپسول سوکسیمر ۱۰۰ میلیگرم
- 07913 · SUCCIMER 200MG CAP · کپسول سوکسیمر ۲۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Chemet · 3FDA Chemet · 2.2FDA Chemet · 2.1FDA Chemet · 2.3FDA Chemet · 4FDA Chemet · 5FDA Chemet · SPL approval / marketing categoryFDA Chemet · 8.1FDA Chemet · 8.2FDA Chemet · 8.4FDA Chemet · 8.3
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1985/Succimer
- Clinical review⚠ Unverified