Degarelix

دگارلیکس

⚠ Unverified

🎗️ Antineoplastic And Immunomodulating AgentsGnRH antagonist

Market / country: 🇺🇸 USA

Firmagon (US)

🧮 Dose calculator

Prostate cancer · Regimen source: FDA Firmagon · 2.1

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

Warnings

  • • Hypersensitivity reactions; QT prolongation; embryo-fetal toxicity. FDA Firmagon · 5

Formulations

  • 120 mg vial (starting dose = 2 vials) — powder for injection 🇺🇸 USA FDA Firmagon · 3
  • 80 mg vial (maintenance) — powder for injection 🇺🇸 USA FDA Firmagon · 3

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Firmagon · 8.1

    “Based on findings in animal studies and mechanism of action, FIRMAGON can cause fetal harm and loss of pregnancy when administered to a pregnant woman [ see Clinical Pharmacology (12.1) ].”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Firmagon · 8.2

    “The safety and efficacy of FIRMAGON have not been established in females.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Firmagon · 8.4

    “Safety and effectiveness in pediatric patients have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Firmagon · 8.5

    “Of the total number of subjects in clinical studies of FIRMAGON, 82% were age 65 and over, while 42% were age 75 and over.”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Firmagon · 8.3

    “Infertility Based on findings in animals and mechanism of action, degarelix may impair fertility in males and females of reproductive potential [see Nonclinical Toxicology (13.1) ].”

📚 Reference status for this drug

Shows which sources have references recorded for this drug and which do not.

🔗 Similar drugs

For the same diseases

Doz is only a support tool and does not replace clinical judgment or official sources. Check every dose against the original source before prescribing. About & disclaimer · Sources

Information on this site is compiled from online websites and references. Doz accepts no responsibility for self-medication without approval from a physician and a reliable reference, or for any consequences of using this information.

Inspired by the Saphira project; part of the content is taken from it.

For suggestions, corrections, adding drugs or anything else, you can contact me on Telegram: @cenaav