Degarelix
دگارلیکس
🎗️ Antineoplastic And Immunomodulating AgentsGnRH antagonist
Market / country: 🇺🇸 USA
Firmagon (US)
🧮 Dose calculator
Prostate cancer · Regimen source: FDA Firmagon · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ History of severe hypersensitivity to degarelix. FDA Firmagon · 4
Warnings
- • Hypersensitivity reactions; QT prolongation; embryo-fetal toxicity. FDA Firmagon · 5
Formulations
- 120 mg vial (starting dose = 2 vials) — powder for injection 🇺🇸 USA FDA Firmagon · 3
- 80 mg vial (maintenance) — powder for injection 🇺🇸 USA FDA Firmagon · 3
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Firmagon · 8.1
“Based on findings in animal studies and mechanism of action, FIRMAGON can cause fetal harm and loss of pregnancy when administered to a pregnant woman [ see Clinical Pharmacology (12.1) ].”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Firmagon · 8.2
“The safety and efficacy of FIRMAGON have not been established in females.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Firmagon · 8.4
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Firmagon · 8.5
“Of the total number of subjects in clinical studies of FIRMAGON, 82% were age 65 and over, while 42% were age 75 and over.”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Firmagon · 8.3
“Infertility Based on findings in animals and mechanism of action, degarelix may impair fertility in males and females of reproductive potential [see Nonclinical Toxicology (13.1) ].”
🔗 Reference links
- FDA (approval record)NDA022201
- DailyMed (FDA label)FDA Firmagon
- MedlinePlus (NIH)Degarelix Injection
- WHO ATC/DDDL02BX02
- Darooyab (Iran)❌ None
🇮🇷 Not found in Iran list Darooyab · search
Darooyab lists no registered dosage form or brand for this drug. This does not prove it is unavailable.
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Firmagon · 3FDA Firmagon · 2.1FDA Firmagon · 4FDA Firmagon · 5FDA Firmagon · SPL approval / marketing categoryFDA Firmagon · 8.1FDA Firmagon · 8.2FDA Firmagon · 8.4FDA Firmagon · 8.5FDA Firmagon · 8.3
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · search
- Clinical review⚠ Unverified