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Sulfamethoxazole-trimethoprim (co-trimoxazole)
کوتریموکسازول (سولفامتوکسازول/تریمتوپریم)
💊 AntibioticsSulfonamide + dihydrofolate reductase inhibitor
Market / country: 🇺🇸 USA
Bactrim (US) · Septra (US)
🧮 Dose calculator
Urinary tract infection · Regimen source: FDA TMP-SMX susp · Dosage and Administration
- • Dose is calculated and shown as the trimethoprim component. FDA TMP-SMX susp · Dosage and Administration
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Known hypersensitivity to trimethoprim or sulfonamides. FDA TMP-SMX susp · Contraindications
- ⛔ Pediatric patients less than 2 months of age. FDA TMP-SMX susp · Contraindications
- ⛔ History of drug-induced immune thrombocytopenia, folate-deficiency megaloblastic anemia, marked hepatic damage, severe renal insufficiency without monitoring, concomitant dofetilide. FDA TMP-SMX susp · Contraindications
Renal adjustment
- • eGFR < 30: CrCl 15–30 mL/min: half the usual regimen. FDA TMP-SMX susp · Dosage and Administration
- • eGFR < 15: CrCl below 15 mL/min: use not recommended. FDA TMP-SMX susp · Dosage and Administration
Formulations
- TMP 40 mg + SMX 200 mg / 5 mL — suspension 🇺🇸 USA FDA TMP-SMX susp · How Supplied
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA TMP-SMX susp · How SuppliedFDA TMP-SMX susp · Dosage and AdministrationFDA TMP-SMX susp · Indications and UsageFDA TMP-SMX susp · Contraindications
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Clinical review⚠ Unverified