Chlorambucil

🧮 Dose calculator

Chronic lymphocytic leukaemia (CLL) · Regimen source: FDA Leukeran · Dosage and Administration

• • Usually 4–10 mg/day; whole dose at once. Adjust to response and counts; reduce if counts fall. FDA Leukeran · Dosage and Administration

Enter age and weight.

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Leukeran · Pregnancy

  “Chlorambucil can cause fetal harm when administered to a pregnant woman.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Leukeran · Lactation

  “Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from chlorambucil, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Leukeran · Pediatric Use

  “The safety and effectiveness in pediatric patients have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Leukeran · Geriatric Use

  “In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.