Cefotaxime (injection)
سفوتاکسیم (تزریقی)
🦠 Antiinfectives For Systemic UseThird-generation cephalosporin
Market / country: 🇺🇸 USA
Claforan (US)
🧮 Dose calculator
Sepsis / serious hospital infection (refer) · Regimen source: FDA Claforan · Dosage and Administration
🛡️ Safety & information
Contraindications
- ⛔ Cephalosporin hypersensitivity; caution with penicillin allergy. FDA Claforan · Contraindications
Formulations
- 1 g vial (IM/IV after reconstitution) — powder for injection 🇺🇸 USA FDA Claforan · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Claforan · Precautions/Warnings – Pregnancy
“Category B: Reproduction studies have been performed in pregnant mice given CLAFORAN intravenously at doses up to 1200 mg/kg/day (0.4 times the recommended human dose based on mg/m 2 ) or in pregnant rats when administered intravenously at doses up to 1200 mg/kg/day (0.8 times the recommended human dose based on mg/m …”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Claforan · Precautions/Warnings – Nursing Mothers
“Caution should be exercised when CLAFORAN is administered to a nursing woman.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Claforan · Precautions/Warnings – Pediatric Use
“See Precautions above regarding perivascular extravasation.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Claforan · Precautions/Warnings – Geriatric Use
“Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function (see PRECAUTIONS, General ).”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA050547
- DailyMed (FDA label)FDA Claforan
- MedlinePlus (NIH)Cefotaxime Injection
- WHO ATC/DDDJ01DD01
- Darooyab (Iran)Cefotaxime
🇮🇷 Registered in Iran Darooyab · G-335/Cefotaxime
Dosage forms with Iranian generic codes, per Darooyab.
- 01336 · CEFOTAXIME 1GR VIAL · ویال سفوتاکسیم ۱ گرم
- 13637 · CEFOTAXIME 2GR VIAL · ویال سفوتاکسیم ۲ گرم
- 00229 · CEFOTAXIME 500MG VIAL · ویال سفوتاکسیم ۵۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Claforan · How SuppliedFDA Claforan · Dosage and AdministrationFDA Claforan · ContraindicationsFDA Claforan · SPL approval / marketing categoryFDA Claforan · Precautions/Warnings – PregnancyFDA Claforan · Precautions/Warnings – Nursing MothersFDA Claforan · Precautions/Warnings – Pediatric UseFDA Claforan · Precautions/Warnings – Geriatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-335/Cefotaxime
- Clinical review⚠ Unverified