Bleomycin
بلئومایسین
🎗️ Antineoplastic And Immunomodulating AgentsAntitumour antibiotic
Market / country: 🇺🇸 USA
Blenoxane (US)
🧮 Dose calculator
Testicular cancer · Regimen source: FDA Bleomycin · Dosage and Administration
- • Only under an oncologist in an equipped centre. Calculator = label mg/m² × BSA (Mosteller); protocol, cycle interval and adjustment for CBC and renal/hepatic function rest with the oncology team. FDA Bleomycin · Dosage and Administration
- • Calculator gives the lower bound. Lymphoma: first 2 doses 2 units or less (anaphylactoid reaction). Pulmonary toxicity rises sharply above 400 units total. FDA Bleomycin · Dosage and Administration
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Prior hypersensitive or idiosyncratic reaction to bleomycin. FDA Bleomycin · Contraindications
Warnings
- • Pulmonary toxicity (pneumonitis to fibrosis, about 10%); idiosyncratic anaphylaxis-like reactions in lymphoma; caution in renal or pulmonary impairment. FDA Bleomycin · Warnings
Formulations
- 30 units vial (also 15 units) — powder for injection 🇺🇸 USA FDA Bleomycin · How Supplied
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Bleomycin · Pregnancy “Category D”
“Bleomycin can cause fetal harm when administered to a pregnant woman.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Bleomycin · Nursing Mothers
“Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, it is recommended that nursing be discontinued by women receiving bleomycin therapy.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Bleomycin · Pediatric Use
“Safety and effectiveness of bleomycin in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Bleomycin · Geriatric Use
“Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA205030
- DailyMed (FDA label)FDA Bleomycin
- MedlinePlus (NIH)Bleomycin
- WHO ATC/DDDL01DC01
- Darooyab (Iran)Bleomycin-Sulfate
🇮🇷 Registered in Iran Darooyab · G-956/Bleomycin-Sulfate
Dosage forms with Iranian generic codes, per Darooyab.
- 00170 · BLEOMYCIN SULFATE 15MG VIAL · ویال بلئومایسین سولفات ۱۵ میلیگرم
- 19196 · BLEOMYCIN SULFATE 5MG INJ · فرآورده تزریقی بلئومایسین سولفات ۵ میلیگرم
- 52471 · BLEOMYCIN INJECTION PARENTERAL 15 [iU] · فرآورده تزریقی بلئومایسین ۱۵ واحد بینالمللی
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Bleomycin · How SuppliedFDA Bleomycin · Dosage and AdministrationFDA Bleomycin · ContraindicationsFDA Bleomycin · WarningsFDA Bleomycin · Pregnancy “Category D”FDA Bleomycin · Nursing MothersFDA Bleomycin · Pediatric UseFDA Bleomycin · Geriatric UseFDA Bleomycin · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-956/Bleomycin-Sulfate
- Clinical review⚠ Unverified