Bleomycin

بلئومایسین

⚠ Unverified

🎗️ Antineoplastic And Immunomodulating AgentsAntitumour antibiotic

Market / country: 🇺🇸 USA

Blenoxane (US)

🧮 Dose calculator

Testicular cancer · Regimen source: FDA Bleomycin · Dosage and Administration

  • • Only under an oncologist in an equipped centre. Calculator = label mg/m² × BSA (Mosteller); protocol, cycle interval and adjustment for CBC and renal/hepatic function rest with the oncology team. FDA Bleomycin · Dosage and Administration
  • • Calculator gives the lower bound. Lymphoma: first 2 doses 2 units or less (anaphylactoid reaction). Pulmonary toxicity rises sharply above 400 units total. FDA Bleomycin · Dosage and Administration

Enter age and weight.

🛡️ Safety & information

Contraindications

Warnings

  • • Pulmonary toxicity (pneumonitis to fibrosis, about 10%); idiosyncratic anaphylaxis-like reactions in lymphoma; caution in renal or pulmonary impairment. FDA Bleomycin · Warnings

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Bleomycin · Pregnancy “Category D”

    “Bleomycin can cause fetal harm when administered to a pregnant woman.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Bleomycin · Nursing Mothers

    “Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, it is recommended that nursing be discontinued by women receiving bleomycin therapy.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Bleomycin · Pediatric Use

    “Safety and effectiveness of bleomycin in pediatric patients have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Bleomycin · Geriatric Use

    “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

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