Bempedoic acid

🧮 Dose calculator

Hyperlipidemia / heterozygous familial hypercholesterolemia · Regimen source: FDA Nexletol · 2.1

• • Check lipids 8–12 weeks after starting. FDA Nexletol · 2.1

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Nexletol · 8.1

  “NEXLETOL decreases cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterol; therefore, NEXLETOL may cause fetal harm when administered to pregnant women based on the mechanism of action [see Clinical Pharmacology (12.1) ] .”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Nexletol · 8.2

  “Risk Summary Bempedoic acid was detected in breast milk of lactating women who received six consecutive daily doses of 180 mg bempedoic acid.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Nexletol · 8.4

  “The safety and effectiveness of NEXLETOL have not been established in pediatric patients.”

• 👴 Older adultsNo specific problem stated

  Label: no specific difference or dose adjustment stated for older adults. FDA Nexletol · 8.5

  “No overall differences in safety or effectiveness of NEXLETOL have been observed between patients 65 years of age and older and younger adult patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.