Asenapine

آسناپین

⚠ Unverified

🧠 Nervous SystemAtypical antipsychotic

Market / country: 🇺🇸 USA

Saphris (US)

🧮 Dose calculator

Schizophrenia · Regimen source: FDA Saphris · 2.2

  • • Dissolve under the tongue; do not chew or swallow; no food or drink for 10 min. Increase to 10 mg after one week if tolerated; no added benefit shown. FDA Saphris · 2.2FDA Saphris · 2.1

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Severe hepatic impairment (Child-Pugh C); history of hypersensitivity to asenapine (anaphylaxis, angioedema). FDA Saphris · 4

Warnings

  • • Boxed warning: increased mortality in elderly patients with dementia-related psychosis — not approved for this use. FDA Saphris · Boxed Warning
  • • Neuroleptic malignant syndrome; tardive dyskinesia; metabolic changes; hyperprolactinaemia; seizures; dysphagia; falls. FDA Saphris · 5

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Saphris · 8.1

    “Risk Summary Neonates exposed to antipsychotic drugs during the third trimester of pregnancy are at risk for extrapyramidal and/or withdrawal symptoms.”
  • 🤱 BreastfeedingNo data

    The source for this drug has no section for this group.

  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Saphris · 8.4

    “Safety and efficacy of SAPHRIS in pediatric patients below the age of 10 years of age have not been evaluated.”
  • 👴 Older adultsDangerous / avoid

    Label: serious warning or avoid in older adults. FDA Saphris · Boxed Warning

    “Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

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