Argatroban

🧮 Dose calculator

Heparin-induced thrombocytopenia (HIT) · Regimen source: FDA Argatroban · 2.2

• • Stop heparin and get a baseline aPTT. Adjust to aPTT 1.5–3× baseline (not >100 s); max 10 mcg/kg/min. Moderate/severe hepatic impairment: lower dose. FDA Argatroban · 2.2FDA Argatroban · 2.4

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Argatroban · 8.1

  “Risk Summary Limited data from published literature and postmarketing reports do not suggest an association between argatroban and adverse fetal outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Argatroban · 8.2

  “There are no data on the presence of argatroban in human milk, or its effects on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Argatroban · 8.4

  “Safety and effectiveness have not been established in pediatric patients.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Argatroban · 8.5

  “The safety analysis did suggest that older patients tended to have an increased risk of events compared to younger patients; however, older patients had increased underlying conditions, which may predispose them to adverse reactions.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.