Bivalirudin

بیوالیرودین

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🩸 Blood And Blood Forming OrgansDirect thrombin inhibitor

Market / country: 🇺🇸 USA

Angiomax (US)

🧮 Dose calculator

Acute coronary syndrome / post-MI · Regimen source: FDA Bivalirudin · 2.1

  • • The calculator gives the BOLUS. Check ACT after 5 min; extra 0.3 mg/kg bolus if needed. Studied only with aspirin. Infusion may continue up to 4 h after PCI. FDA Bivalirudin · 2.1

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🛡️ Safety & information

Contraindications

Renal adjustment

  • • eGFR < 30: CrCl <30: infusion 1 mg/kg/h; haemodialysis: 0.25 mg/kg/h. No change to the bolus. FDA Bivalirudin · 2

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Bivalirudin · 8.1

    “Risk Summary There are no data available on use of bivalirudin in pregnant women to inform a drug-associated risk of adverse developmental outcomes.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Bivalirudin · 8.2

    “No data are available on the effects on the breastfed child or on milk production.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Bivalirudin · 8.4

    “The safety and effectiveness of bivalirudin in pediatric patients have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Bivalirudin · 8.5

    “In studies of patients undergoing PCI, 44% were ≥65 years of age and 12% of patients were ≥75 years old.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

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