Zoledronic acid (yearly)

🧮 Dose calculator

Osteoporosis / calcium and vitamin D deficiency · Regimen source: FDA Reclast · 2.2FDA Reclast · 2.3

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Reclast · 8.1

  “Discontinue Reclast when pregnancy is recognized.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Reclast · 8.2

  “Risk Summary There are no data on the presence of zoledronic acid in human milk, the effects on the breast-fed infant, or the effects on milk production.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Reclast · 8.4

  “Reclast is not indicated for use in children.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Reclast · 8.5

  “However, because decreased renal function occurs more commonly in the elderly, special care should be taken to monitor renal function.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Reclast · 8.3

  “Infertility There are no data available in humans.”